N-acetylcysteine overdose after acetaminophen poisoning

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N-Acetylcysteine Overdose After Acetaminophen Poisoning

N-acetylcysteine (NAC) is a drug  used  widely and effectively in oral  and  ‎intravenous  forms  as  a  specific  antidote  for acetaminophen poisoning.  In children ‎considering the toxic dose of acetaminophen ingested by the patient and the body weight, the ‎physician prescribes a specific dose of NAC. There is always a risk of  iatrogenic overdose of  ‎NAC  which can cause different mild to...

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N-acetylcysteine overdose after acetaminophen poisoning

N-acetylcysteine (NAC) is used widely and effectively in oral and intravenous forms as a specific antidote for acetaminophen poisoning. Here we report a rare case of iatrogenic NAC overdose following an error in preparation of the solution, and describe its clinical symptoms. Laboratory results and are presented and examined. A 23-year-old alert female patient weighing 65 kg presented to the em...

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Acetaminophen overdose and N-acetylcysteine therapy.

Dear Editor, I read with interest the case report by Sule et al,1 published in the February 2006 issue of the journal. They reported a case of massive ingestion of paracetamol, successfully managed by a 3-day infusion of N-acetylcysteine. They concluded that a modified 3-day regime is safe and efficacious. Prolonged infusion of N-acetylcysteine for treatment of significant acetaminophen overdos...

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Acetylcysteine for acetaminophen poisoning.

This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the author’s clinical r...

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ژورنال

عنوان ژورنال: International Medical Case Reports Journal

سال: 2015

ISSN: 1179-142X

DOI: 10.2147/imcrj.s74563